Monitoring and analysis of iodine nutrition status among children aged 8 - 10 years in Shenzhen

Acta Universitatis Medicinalis Anhui 2025, 12, v.60 2333-2337+2345     font:big middle small

Fund programs: National Natural Science Foundation of China ( No . 22176132) ; Shenzhen Medical Research Fund (No . B2403008) ; Project of Shenzhen Science and Technology Innovation Commission (No . JCYJ20210324135000001) ; Guangdong Medical Science Research Fund (No . A2023276)

Authors:Zhou Chenyu1 , 2 , Chen Yang2 , 3 , Zhu Lu1 , 2 , Kong Lingquan2 , Zhuo Lan2 , Wang Zhou2 , Luo Xianru2 , Song Jiayi2 , Zhang Jianqing1 , 2 , 3

Keywords:iodine deficiency disorders; iodine nutrition; children; thyroid volume; salt iodine; urinary iodine;

DOI:10.19405/j.cnki.issn1000-1492.2025.12.017

〔Abstract〕 Objective To investigate the iodine nutrition status of children aged 8 - 10 in Guangming , Longhua vention strategies and to provide a scientific basis for the elimination of iodine deficiency disorders. Methods Urine and household salt samples were randomly collected from 580 non⁃boarding students aged 8 - 10 years for iodine content detection. Thyroid volume was measured using a fully digital ultrasound imaging system , and goiter prevalence was calculated. Results A total of 580 samples was tested. The median salt iodine concentration was 23. 86 mg/kg , with 93. 62% qualified iodized salt and 94. 48% coverage rate. The median of urinary iodine was 265. 00 μg/L , mainly distributed between 200 - < 300 μg/L and ≥300 μg/L. The proportion of children with ap⁃ propriate iodine was 20. 86% , and the proportion of children with insufficient or excessive urinary iodine levels was 10. 86% and 68. 28% of the total surveyed population , respectively. The median thyroid volume was 3. 27 mL , and the goiter rate was 1. 72% . Multiple linear regression analysis showed that age was the risk factor for thyroid volume (β=0. 328, P <0. 05), while urinary iodine was the protective factor for thyroid volume (β= -4. 134 x10-4, P <0. 05). Conclusion The qualified iodized salt rate, median of urinary iodine, and goiter prevalence of580 children aged 8 - 10 meet the elimination cniteria for iodine deficiency disorders. Age and urinary iodine areclosely related to thyrid volume change. The urinary iodine level of children is generally high and requires seriousattention.